Founders often treat SBIR and STTR as the same program with different letters. They are close, both are US-only, small-business R&D programs, both fund at roughly the same levels, and both are non-dilutive, but the difference decides who does the work and, often, whether you win.
STTR requires a partner research institution, a university or a federal lab, that performs at least 30% of the project. Your company must do at least 40%. SBIR has no such requirement: the small business must perform at least two-thirds of Phase I itself, and any research institution is an optional subcontractor.
So the question is simple. Does your technology lean on a specific lab, a professor's instrument, or university IP you want to license? STTR formalizes that partnership and pays for it. Is your team self-contained with the expertise in-house? SBIR keeps more of the work, and the money, under your roof.
Quick test: If removing your university partner would kill the project, you probably belong in STTR. If the partner is just "nice to have," SBIR keeps more money and control in your company.
See if you qualify for an Ansys eval The MVP playbook →At NASA, both run through the same rolling Broad Agency Announcement and land in the same neighborhood: Phase I around $150,000 (up to roughly $225K-$275K by appendix) for a feasibility study, and Phase II up to roughly $850,000 for development. Neither requires cost share. Neither takes equity. Both can graduate into a Phase III that has no dollar cap and can be sole-sourced into a real NASA contract.
The classic STTR mistake is bolting on a university partner just to check the box, then discovering the institution's tech-transfer office needs months to sign an allocation-of-rights agreement. If you go STTR, lock the partnership and the IP terms before you write the proposal. The classic SBIR mistake is the opposite, subcontracting so much work that you fall below the two-thirds threshold and get bounced on compliance.
Both are the friendliest entry point in NASA's funding stack: full funding, no match, no dilution, and a direct line to Phase III. Choose based on where the work actually happens, not on which acronym sounds bigger. Then register in SAM.gov early, because an inactive registration will sink either one.
Read the official program definitions before you commit at nasa.gov/sbir_sttr.